Protein Details: Gap junction alpha-10 protein

Protein ID

ICDB_Pro_1701

Protein Name

Gap junction alpha-10 protein

Gene Name

Gja10

Organism

Mus musculus (Mouse)

Length

505 amino acids

AlphaFoldDB

AF-Q9WUS4-F1-model_v4.pdb

Function

Sequence

MGDWNLLGGILEEVHSHSTIVGKIWLTILFIFRMLVLGVAAEDVWDDEQSAFACNTQQPGCNNICYDDAFPISLIRFWVLQIIFVSSPSLVYMGHALYRLRDFEKQRQKKKLYLRAQMENPELDLEEQQRVDKELRRLEEQKRIHKVPLKGCLLRTYVLHILTRSVLEVGFMIGQYILYGFQMHPIYKCTQAPCPNSVDCFVSRPTEKTIFMLFMHSIAAISLLLNILEIFHLGIRKIMRALDGKSSSGNTENETGPPFHSTNYSGTQQCMICSSLPERISLLQANNKQQVIRVNIPRSKSMWQIPHPRQLEVDVSCGKRDWAEKIESCAQLHVHSPCPHDRSARIQHPGQQPCHSVFGPKNAMSQSWFGTMTASQHRPSSALETWERSQGPEASGRSLTDRQSHFQGSDGSARESGVWTDRLGPGSRKASFLSRLMSEKGQRHSDSGSSRSLNSSCLDFSHGENSPSPLPSATGHRASMVSKSSHVDSPPHSSFIIHETYVYVY

PDB Structures

Ligand Binding

1. DICL_CP

2. DICL_Pep

Binding Site

Disease

Location

Low levels were detected in skin; heart; kidney; testis; ovary; intestine. Expression not detected in brain; sciatic nerve or liver. According to PubMed:15147297 expression is detected only in horizontal cells in the inner nuclear layer of the retina and not in other neurons of the central nervous system or tissues. According to PubMed:15147297 expression is detected only in horizontal cells in the inner nuclear layer of the retina and not in other neurons of the central nervous system or tissues. According to PubMed:15147297 expression is detected only in horizontal cells in the inner nuclear layer of the retina and not in other neurons of the central nervous system or tissues. Detected in the outer plexiform layer of the retina (at protein level)

DOI ID

10.1074/jbc.274.21.14716; 10.1371/journal.pbio.1000112; 10.1111/j.0953-816x.2004.03360.x; 10.1080/15419060302063; 10.1111/j.1460-9568.2006.04848.x; 10.1016/j.neuroscience.2007.06.003; 10.1371/journal.pone.0001714

RefSeq

NP_034419.2